Welcome to the MRC Centre for Inflammation Research

State of the Art Imaging

CIR Imaging Suite including confocal microscopy and flow cytometry services. State of the art clinical and small mammal molecular imaging: MRI, CT, PET.

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Scientist training in lab

Training clinical and non-clinical scientists in the molecular, cell and tissue biology of inflammatory and immune processes.

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QMRI building
MRC Centre for Inflammation Research

A multidisciplinary centre of excellence; Internationally outstanding researchers developing novel approaches of diagnosis, prevention and treatment

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Three key thematic areas: Immune Modulation and Regulation of Inflammation; Tissue Remodelling and Regeneration; and Imaging Inflammation.

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Deanery of Clinical Sciences: Athena SWAN Bronze status

The CIR strives to promote a culture of respect and nurtures excellence, leadership and innovation and inclusion of people from all backgrounds

The Athena SWAN Award
Scientist training in lab
QMRI building

The University of Edinburgh / Medical Research Council (MRC) Centre for Inflammation Research (CIR) is a multidisciplinary centre in which clinical and non-clinical scientists prosecute internationally competitive research to identify targets and deliver translational benefits. Additionally, the Centre is a highly fertile environment for the training of scientific and medical graduates in inflammation biology. Our College of Medicine and Veterinary Medicine ranked outstanding in the recent UK REF2014 research assessment.

MRC-CIR Image of the Month

Confocal microscopy image of rat gut dendritic cells (bright green) during acute pancreatitis, with the mucus barrier layer shown in red and cell nuclei in blue. Image from the research group led by Damian Mole at the Centre for inflammation Research. This image was captured using the Leica SP5 microscope at the Queen’s Medical Research Institute.
Acute pancreatitis is caused by a severe inflammatory reaction in the pancreas, which is usually triggered by gallstones or excessive alcohol consumption. Pancreatitis is a paradigm of sterile systemic inflammation. Most patients are admitted to hospital and recover without any specialist treatment. However, one in five people with the condition develop life-threatening complications that require intensive care. These people can need breathing support, tube feeding and sometimes kidney dialysis and one in five of those will die. In carefully controlled studies using mice and rats, the research team led by Damian Mole has identified a treatment which calms inflammation in acute pancreatitis and protects against organ failure caused by the condition.
Further information regards the research undertaken by this research team can be found on:
Damian Mole CIR profile page
A recent publication by the team in the journal Nature Medicine
Details of the microscope used can be found on the Confocal and Advanced Light Microscopy Facility pages.

View more images from MRC-CIR.
This page was last modified on 25 November, 2015