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Welcome to the MRC Centre for Inflammation Research
The University of Edinburgh / Medical Research Council (MRC) Centre for Inflammation Research (CIR) is a multidisciplinary centre in which clinical and non-clinical scientists prosecute internationally competitive research to identify targets and deliver translational benefits. Additionally, the Centre is a highly fertile environment for the training of scientific and medical graduates in inflammation biology. Our College of Medicine and Veterinary Medicine ranked outstanding in the recent UK REF2014 research assessment.
MRC-CIR Image of the Month FEBRUARY 2016
Confocal microscopy image of rat gut dendritic cells (bright green) during acute pancreatitis, with the mucus barrier layer shown in red and cell nuclei in blue. Image from the research group led by Damian Mole at the Centre for inflammation Research. This image was captured using the Leica SP5 microscope at the Queen’s Medical Research Institute.
Acute pancreatitis is caused by a severe inflammatory reaction in the pancreas, which is usually triggered by gallstones or excessive alcohol consumption. Pancreatitis is a paradigm of sterile systemic inflammation. Most patients are admitted to hospital and recover without any specialist treatment. However, one in five people with the condition develop life-threatening complications that require intensive care. These people can need breathing support, tube feeding and sometimes kidney dialysis and one in five of those will die. In carefully controlled studies using mice and rats, the research team led by Damian Mole has identified a treatment which calms inflammation in acute pancreatitis and protects against organ failure caused by the condition.
Further information regards the research undertaken by this research team can be found on:
Damian Mole CIR profile page
A recent publication by the team in the journal Nature Medicine
Details of the microscope used can be found on the Confocal and Advanced Light Microscopy Facility pages.
MRC-CIR Engaging with the Public: Lighting up the Lungs
Dr Kev Dhaliwal of MRC-CIR and the Proteus Project will be presenting on the topic of visualising disease in the 'Lets Talk about Health lecture series'. The series of talks is a chance for anyone who is interested in health research to learn more about the progress we are making towards better treatments and as an added bonus this year guests will have an opportunity to tour the labs and speak to early career scientists.
Doors open for the presentation at 16.30 on Wednesday 16th December with tea and coffee available. Lab tours for school pupils take place between 16.30-17.30 with the main presentation by Dr Dhaliwal and his team starting at 17.30 untill 18.45.
The talk will be held at the Queens Medical Research Institute, 47 Little France Crescent EH16 4TJ and tickets can be booked by clicking here although entry on the day is welcome but on a first come first served basis.
This page was last modified on 25 November, 2015