Welcome to the MRC Centre for Inflammation Research

State of the Art Imaging

CIR Imaging Suite including confocal microscopy and flow cytometry services. State of the art clinical and small mammal molecular imaging: MRI, CT, PET.

Find out more about imaging...
Scientist training in lab

Training clinical and non-clinical scientists in the molecular, cell and tissue biology of inflammatory and immune processes.

Find out more about training...
QMRI building
MRC Centre for Inflammation Research

A multidisciplinary centre of excellence; Internationally outstanding researchers developing novel approaches of diagnosis, prevention and treatment

Read more about research...

Three key thematic areas: Immune Modulation and Regulation of Inflammation; Tissue Remodelling and Regeneration; and Imaging Inflammation.

Find out more about our research...
Athena SWAN silver award logo
Deanery of Clinical Sciences: Athena SWAN Silver status

The CIR strives to promote a culture of respect and nurtures excellence, leadership and innovation and inclusion of people from all backgrounds

The Athena SWAN Award
Scientist training in lab
QMRI building
Athena SWAN silver award logo

The University of Edinburgh / Medical Research Council (MRC) Centre for Inflammation Research (CIR) is a multidisciplinary centre in which clinical and non-clinical scientists prosecute internationally competitive research to identify targets and deliver translational benefits. Additionally, the Centre is a highly fertile environment for the training of scientific and medical graduates in inflammation biology. Our College of Medicine and Veterinary Medicine ranked outstanding in the recent UK REF2014 research assessment.

MRC-CIR Image of the Month
August 2016

Biliary atresia is a devastating condition which causes inflammation and destruction of children’s bile ducts, and can lead to biliary fibrosis (scarring of the liver), liver failure and death. The activation of resident fibroblast cells (mesenchymal cells) within the liver to scar-producing cells (myofibroblasts) is a key process during biliary fibrosis. As a result, a considerable amount of research has focused on trying to better understand this process in a bid to identify potential anti-fibrotic therapeutic targets. 

In this image of mouse biliary fibrosis (taken by Ross Dobie in the Henderson group), mesenchymal (scar-forming) cells are labelled with an intrinsic genetic fluorescent reporter in green, endothelial cells are stained with an endothelial cell specific antibody (CD31) in red, and cell nuclei are labelled with DAPI in blue. This image highlights how scar-producing cells markedly expand in a mouse model of biliary fibrosis.     

View more images from MRC-CIR.
This page was last modified on 12 April, 2016